schimmeldoders en voeding


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Natuurlijke schimmeldoders


Op deze pagina wil ik een overzicht bouwen van natuurlijke schimmeldoders die bijvoorbeeld kunnen helpen bij een overwoekering door Candida schimmel.
Aanvullingen voor deze pagina of ervaringen svp doormailen naar: ugamedia@wirehub.nl

Kennis delen = anderen helpen

Ron


Kokosolie (Caprylzuur)

Kokosolie en schimmelinfecties: maak kom af met Candida albicans.... Niet alleen kan kokosolie onze afhankelijkheid van antibiotica verminderen, kokosolie draagt eveneens bij tot een gezonde balans in onze darmflora. Eťn van de ontmoedigende neveneffecten van medicatie en antibiotica is dat zij niet alleen slechte, maar ook goede bacteriŽn doden en zo tevens schimmelinfecties veroorzaken Landen waar veel kokosnoten gegeten worden zijn meestal landen waar veel schimmels voorkomen. India, Sri Lanka, IndonesiŽ, PolynesiŽ en de Filippijnen zijn zulke landen en opvallend is dat er desondanks weinig schimmelinfecties bij de mensen voorkomen.

Bevat bestanddelen werkzaam tegen bacteriŽn, virussen, schimmels, protozoa, gisten. Het gaat om laurinezuur, capronzuur, caprinezuur, caprylzuur, myristinezuur die samen meer dan 70% uitmaken van de vetzuren van kokosolie. Normaal bestaat 18% van moedermelk uit laurine- en caprinevetzuren die de baby helpen beschermen tegen infecties van schimmels, bacteriŽn, virussen en protozoa. Voor moeders tijdens de zwangerschap is het dus ook erg nuttig om te gebruiken.

http://groups.msn.com/Candidiasis/general.msnw?action=get_
message&mview=0&ID_Message=2735&LastModified=4675559443442356099

http://www.geocities.com/lucasvo/extraviergekokosolie.html


Albizia myriophylla Benth. stem (steel) (Thailand)

Study - screening of Thai medicinal plants for anticandidal activity.

Medicinal plants are often used in the treatment of various ailments. In this study, 23 of Thai medicinal plants were screened for their anticandidal activity against six pathogenic Candida species: C. albicans, C. glabrata, C. guilliermondii, C. krusei, C. parapsilosis and C. tropicalis. The methanol extract of Hibiscus sabdariffa L. fruit, Trigonostemon reidioides (Kurz) Craib root, Usnea siamensis Vain whole plant, Boesenbergia rotunda (L.) Mansf. rhizome, and Albizia myriophylla Benth. stem showed anticandidal activity against one or more species of Candida Among them, A. myriophylla Benth. showed broad anticandidal activity. The susceptibility tests of A. myriophylla Benth. extract, in terms of minimal inhibitory concentrations (MIC) and minimal fungicidal concentration (MFC), were performed by the broth microdilution techniques as described by the Clinical Laboratory Standard Institute. MICs of A. myriophylla Benth. extract to all Candida species was ranged 100-500 mug ml(-1). The killing activity of A myriophylla Benth. extract was fast acting against all Candida tested; the reduction in the number of CFU ml(-1) was >3 log(10) units (99.9%) in 2 h. This study indicates that A. myriophylla Benth. extract has considerable anticandidal activity, deserving further investigation for clinical applications for the treatment of candidiasis.

Rukayadi Y, Shim JS, Hwang JK. Department of Biotechnology, College of Engineering, Yonsei University, Seoul, Korea.


Probiotica

Volgens voormalig WHO-onderzoeker dr. Antonio Constantini spelen ongewenste schimmels een belangrijke rol bij het ‘dichtgroeien’ van kransslagaderen. ‘Schimmels maken in de darm gifstoffen, zogenoemde mycotoxinen,’ verklaart Constantini. ‘Sommige mycotoxinen, ondermeer die van een schimmel die algemeen voorkomt in granen, wekken al in kleine hoeveelheden ernstige aderverkalking op. In een gezonde, evenwichtige darmflora krijgen zulke schadelijke schimmels geen kans. Maar als de balans verstoord raakt, gaan ze woekeren, waardoor er hoge concentraties bloedvat-onvriendelijk gif in het bloed komen. Eťn van de manieren van het lichaam om zich tegen mycotoxinen te beschermen, is de aanmaak van extra cholesterol. Cholesterol maakt gifstoffen minder schadelijk. Probiotica laten een cholesterol≠verlagend effect zien, omdat ze kwalijke darmschimmels en hun gifstoffen temmen, waarna het lichaam de cholesterolproductie omlaag brengt.’

http://www.menshealth.nl/Gezondheid/DossierProbiotica/Dossier
ProbioticaArtikelenNietVerwijderen/Voordelen.htm


Pau d'Arcoboom thee

Al eeuwenlang gebruiken de Zuid-Amerikaanse Indianen de binnenbast van de Pau d'Arcoboom bij verschillende aandoeningen, waaronder diverse infectieziekten. Toen dit middel onder de aandacht van Westerse onderzoekers kwam, werd ontdekt dat het krachtige antiseptische eigenschappen had en zowel tegen virussen, bacteriŽn, schimmels en parasieten effectief bleek, zonder toxisch te zijn voor gezonde lichaamscellen.

Pau d'Arco extract:

  • Bevat naftoquinonen die een krachtige darmzuiverende werking hebben;
  • Verhoogt de weerstand tegen ongunstige micro-organismen en schimmels in de darmen
  • Is goed voor de balans tussen gunstige en ongunstige bacteriŽn in de darmen

http://magazine.vannature.nl/database/stoffen/?s=pau_d_arco
http://www.bonusan.nl/vademecum/pau_d_arco_extract.html


Geelwortel / Curcuma / Turmeric

Er zijn een aantal natuurlijke middelen die van oudsher bekend staan om hun schimmeldodende eigenschappen. Knoflook is er ťťn van. Bij minimaal twee teentjes verse knoflook per dag houden schimmels gťťn stand. Ook aan geelwortel, ui, koriander en venkel hebben ze een grondige hekel. Probeer die zaken dan ook regelmatig door je eten te doen. Ook tijm is een kruid dat bekend staat om z'n schimmeldodende eigenschappen.

http://www.kruidenvrouwtje.nl/dieeten/candida.htm

De volksgeneeskundige toepassingen blijken heel nauw aan te sluiten met wetenschappelijk onderzoek dat de afgelopen jaren heeft plaats gevonden naar het werkingsmechanisme van de plant. De belangrijkste werkzame bestanddelen zijn het curcumine en de etherische oliŽn.

Zo blijken de curcuminen:

• een fungicide werking uit te oefenen tegen onder andere Candida albicans.

• de secretie van gal vermeerderen;
• de stroom van gal naar de darm te bevorderen;
• de lever te beschermen (hepatoprotectivum) en te ondersteunen in zijn functie;
• het gehalte aan glutathion in de lever te verhogen; • de activiteit van glutathion-S-transferase in de lever te stimuleren;
• de detoxificatie van toxische of carcinogene stoffen te bevorderen;
• ontstekingsremmende eigenschappen te hebben;

http://magazine.vannature.nl/database/monografie/Curcuma_longa.pdf


Oregano olie

In een recent onderzoek is de anti-candida werking van oregano olie vergeleken met capryl zuur. Het resultaat was dat oregano meer dan een 100 keer zo sterke anti candida werking heeft dan capryl zuur.

http://www.gardenoflife.nl/Candida.html

 

The body of positive evidence for oregano oil as a major antibiotic is growing. Among 52 plant oils tested, oregano was considered to have "pharmacologic" action against common bugs such as Candida albicans (yeast), E. coli, Salmonella enterica and Pseudomonas aeruginosa. [Journal Applied Microbiology, Volume 86, June 1999] Pseudomonas is a type of germ that is getting more difficult to treat as it has developed strains that are resistant to antibiotic drugs.

http://www.diagnose-me.com/treat/T223028.html

The study's authors concluded that daily consumption of "oregano oil may be highly effective in. the prevention and treatment of candidiasis." The power of the findings led the researchers to suggest that future studies should look at oregano oil against other systemic and skin fungal infections, pathogens and even cancer.

http://findarticles.com/p/articles/mi_m0FKA/is_2_64/ai_83033003


Zwarte walnoot (Juglans nigra)

De olie is een krachtige remedie tegen wormen en schimmels zoals Candida albicans. Daarnaast heeft het een licht laxerende werking, en wordt het wel gebruikt bij huidklachten zoals eczeem en herpes. Het beste kan de olie niet langer dan 3 weken aaneengesloten gebruikt worden. Niet geschikt tijdens de zwangerschap en het geven van borstvoeding.

http://www.vitals.nl/researchItem.asp?IDResearch=22&IDPage=12

Rich in organic tannins, this herb has antifungal and astringent properties which predispose its use for parasitic infections, skin fungi and other skin eruptions.

http://vitanetonline.com/library/Black-Walnut-(Juglans-nigra)


Lactoferrine

Activated lactoferrin and fluconazole synergism against Candida albicans and Candida glabrata vaginal isolates.

The combination of ALF and FCN at the threshold MIC elicited potent synergism, leading to total fungistasis of C albicans and C glabrata vaginal pathogens. ALF is a new class of fungistatic agent with a mode of action distinct from that of azoles.

http://www.ncbi.nlm.nih.gov/pubmed/15568403


Tijm

Dit mediterrane kruid is bijzonder geurig en heeft veel ziektebestrijdende eigenschappen. Het bevat een hoog gehalte aan thymol, een antiseptische olie die goed is voor het bestrijden van infecties aan de luchtwegen. De olie is ook krampstillend, zodat ze goed gebruikt kan worden bij een opgeblazen gevoel. De olie is een krachtig antimycotium. Helpt dus tegen candida. Uitwendig kan het gebruikt worden als kompres voor schimmelinfecties aan de huid.

http://eichr.com/groenten.htm


Zwarte Kummel / Zwarte Komijn

In het Engels noemen ze het:
Black Seed
Black Cumin
Black Caraway
Nigella Sativa (naam van de plant)

Wil je uitgebreidere informatie en meer objectieve informatie (de info op bovengenoemde websites is vaak commercieel), dan zou ik het volgende boek kopen:

The Healing Power of Black Cumin
Auteur: Sylvia Luetjohann
ISBN: 0-914955-53-5
Lotus Light, Shangri-La
http://www.amazingherbs.com/blackseedbooks.html

Ik gebruik zelf de zwarte kummel thee. Er zijn ook capsules en olie van zwarte kummel, maar die verdraag ik minder goed.  De zaadjes (waarvan je thee zet) waar ik de beste ervaringen tot nu toe mee heb, kan je hier bestellen:

http://www.schwarz-kuemmel.de/startpage.html
Ik raad aan van het merk Sasa te bestellen.

Hier vind je meer informatie:
http://www.sweetsunnah.com/blackseed-properties.html
http://www.geocities.com/mutmainaa/food/black_seed.html
http://www.nigella-sativa.com/
http://www.megabust.com/Nigella_Sativa.html
http://www.blackseedusa.com/chemanofblac.html
http://www.amazingherbs.com/blacseedfreq.html
http://www.nooruddinonline.com/history_of_black_seed.htm
http://www.internatural-alternative-health.com/SCAT/THERAMUNEBLACK_5011.cfm

Bobby


Artikelen over Candida


Reakties lezers


Beste Ron

Allicine is de actieve stof die voorkomt uit de knoflook en de meest krachtige werking schijnt te hebben. Dit was voorheen niet te extraheren, nu wel bij het volgende product. In amerika zijn er ook een aantal andere varianten die in medische studies gebruikt worden als krachtig antibioticum in de testfase. Hier een nederlandse leverancier, wel duur, maar staat gelijk aan 50 tenen knoflook. Zou ook een goeie zijn tegen Candida.

http://www.allimax.nl/frame/frame.html

Gregory

 

 


Big pharma


Fluconazole/nystatin

Fluconazole was as safe and effective as nystatin in controlling yeast colonization and in preventing superficial and invasive candida infections and the empirical use of amphotericin B in children and adolescents undergoing intensive chemotherapy for cancer.

http://jac.oxfordjournals.org/cgi/content/abstract/40/6/855

 


Leesvoer


Discovery may lead to better Candidiasis drug

Oral biologists at the University at Buffalo have shown for the first time how histatin, the naturally occurring antifungal agent in saliva, kills the oral pathogen Candida albicans, the fungus responsible for most HIV-related oral infections. Researchers led by Mira Edgerton, D.D.S., Ph.D., discovered that histatin binds to a specific membrane protein called TRK1p, which regulates potassium ion flow through the cell membrane of the pathogenic fungus Candida albicans and allows the cell to regulate its volume.

The binding action of histatin acts like a "foot in the door," said Edgerton, UB research associate professor of oral biology in the UB School of Dental Medicine and senior author on the study. "Blocking the channel open allows a lethal unregulated flow of potassium and other essential molecules into, and out of, the cell. "This is the first identification of a specific target for histatin," she said. "The finding paves the way for eventually developing a better therapeutic drug for candidiasis." Results of the research were presented today (March 11, 2005) at the International Association on Dental Research General Session being held in Baltimore. Candidiasis also is known as thrush, a disease characterized by whitish spots and ulcers on the membranes of the mouth, tongue and throat. It affects primarily people with weakened immune systems caused by antibiotics, chemotherapy or by diseases such as AIDS. Thrush also affects many denture wearers.

The condition can be treated with antifungal medication in otherwise healthy people, said Edgerton, but it is difficult to treat in persons with compromised immunity and can be deadly if it infects vital organs. Researchers were aware that histatin usually can keep Candida albicans in check in persons with enough saliva and a healthy immune system, but they did not know precisely how histatin accomplished this. "There are many types of naturally occurring proteins, such as venoms and toxins, that kill cells by creating holes in the cell membrane," said Edgerton, "but we thought that wasn't the case with histatin. We didn't think it acted in the same way. And we wanted to know why it acts on yeast (fungus is a type of yeast) and not on other types of cells. " Through a series of studies, the researchers identified the target-binding protein on Candida albicans by creating mutant strains of the fungus without the target and exposing the mutants to histatin. Results showed that histatin was significantly less active when the suspect target was missing.

Further research indicated that histatin binding to the target protein killed the fungal cells by preventing it from regulating its ions, the positive and negative charged molecules that move into, and out of, cells. Ions regulate electrostatic pressure between the cells' internal and external environments, which, in turn, regulates their volume and water content. Cells that lose their water content without being able to regulate its re-uptake die rapidly, Edgerton said. "Now that the target for histatin has been identified, we can design a better protein that will be even more effective in binding and holding the channel open, causing even better and more rapid killing of the fungus," said Edgerton. "In addition, many other pathogenic fungi that cause disease in elderly individuals or AIDS patients also should be able to be killed by histatins or drugs designed to target their potassium channels."

 

 

Men do not cause yeast infections in women

Researchers find oral sex, masturbating linked to recurrent infections

Women may blame their husbands or boyfriends for headaches, tears and stress. But they can't be blamed for those nasty recurrent yeast infections, contrary to popular belief.  A new study by University of Michigan Health System researchers finds that the presence of yeast in male sex partners do not make women more prone to recurrent yeast infections. Certain sexual activities, however, were linked to increased risk of recurrent yeast infections in women, according to the study.

"Many physicians, and many women, believe that women get recurrent yeast infections because their partner passes the yeast back to them during intercourse. This study refutes that belief," says study author Barbara Reed, M.D., M.S.P.H., professor of Family Medicine at the U-M Medical School. "This study suggests the risk for recurrent infections is related to something else – perhaps the woman's immune response to the yeast." Candida vulvovaginitis, or yeast infection, is one of the most common diagnoses in American women. About three-quarters of women will have at least one yeast infection in their lives, and 40 percent have recurrent infections. The Candida yeast are often found in both women and men in the genital area, rectum and mouth.

In the study, published in the December Journal of Women's Health, researchers looked at 148 women with confirmed Candida vulvovaginitis and 78 of their male sexual partners. Each woman was examined by a doctor, who collected samples from the vagina, cervix, vulva, tongue and rectum. The men were asked to collect at home urine, fecal and semen samples and a tongue swabbing. The samples were analyzed by culture to determine whether Candida species were present at each site. The women received treatment for their initial infection and were asked to return for follow-up visits after two weeks, four weeks, six months and a year. At each visit, they were asked about symptoms, sexual activity and changes in risk factors. Doctors repeated the pelvic exam and specimen collections.

The women were also told to return for testing any time they had symptoms of vaginal discharge, itching or odor. Doctors performed an exam and collected specimens at these visits as well. After the symptomatic visits, the men were also asked for new specimen collections. Thirty-three of the women developed at least one recurrent yeast infection within the year. At the two-week and one-month visits, none of the women had symptoms of a yeast infection. But 20 percent had a positive culture for Candida in the vaginal area at the two-week visit and 29 percent tested positive for Candida after one month. The researchers found these women were no more likely to develop recurrent infections by the end of the one-year study period.

Among the men, nearly half tested positive for Candida species on the tongue and in the feces, while few showed Candida in their urine or semen. Researchers found no link between Candida in the men's specimens and Candida at the women's vulva, rectum or tongue. They also found no link between recurrent yeast infections and signs of Candida at any site in either the men or women. When sexual activities were looked at, however, the researchers found women who had recurrences were more likely to have participated in cunnilingus (or oral sex given to the woman) or masturbation of the woman with saliva in the past month. Only 14.5 percent of women reported masturbation with saliva, however, while 69 percent reported cunnilingus, suggesting oral sex is the more common risk. Oral sex and masturbation with saliva proved to be risk factors whether men showed signs of yeast in their mouth or not. The risk was also not affected by the presence of Candida in the women's genital area. "We're not saying that oral sex is a problem for everyone, but if a women is experiencing recurrent yeast infections, those activities put her at an increased risk," Reed says. The woman's age at first intercourse, lifetime number of partners, frequency of intercourse or anal intercourse in the previous month were all not associated with recurrences. The researchers suggest that Candida exists in some women in balance with the other organisms and immune components in the vaginal area, and that washing that area with saliva may disrupt the balance, leading to symptoms of yeast infection.

 

 

Yeast finding links processes in heart disease and cancer

By studying a little-known yeast too primitive to get diseases, Johns Hopkins researchers have uncovered a surprising link between two processes at play in heart disease and cancer in people.In experiments with yeast known as S. pombe, the researchers discovered that a gene that helps the organism make cholesterol also helps it survive when oxygen is scarce. The finding, described in the March 25 issue of Cell, offers a new strategy for killing infectious yeast, but it also suggests that cells' efforts to make cholesterol and detect oxygen levels might be connected in people, too.

"We were simply trying to establish that this yeast could be a model for studying cholesterol-related activities in human cells," says the study's leader, Peter Espenshade, Ph.D., assistant professor of cell biology in Johns Hopkins' Institute for Basic Biomedical Sciences. "We certainly didn't expect to find a completely new role for this gene." It's already well established that human cells can both make cholesterol and sense oxygen. In people, high levels of cholesterol in the blood are a major risk factor for heart disease, and many human cancer cells are able to survive despite being in tumors' oxygen-starved centers.

"We don't know yet whether cholesterol production and oxygen sensing are connected in human cells, but now we're trying to find out," says Espenshade. In people, the gene in question, known as SREBP, controls other genes whose products help make or import cholesterol. Cholesterol-lowering drugs called statins mimic this gene's natural role by triggering cells to import more cholesterol, clearing the artery-clogging stuff from the blood. Despite the obvious medical relevance of SREBP, no one had ever looked at the equivalent system -- or even determined whether there was one -- in yeast, the simple, single-celled relatives with which we share many genes. Because yeast can be easily manipulated and studied, Espenshade figured they might be a good model for figuring out exactly how SREBP is turned on, what it does and how it's shut off -- if the organism has an equivalent process. Turning first to databases of the entire genetic sequences of various yeast, Espenshade sought yeast genes that looked like SREBP and its binding partner SCAP. Nothing turned up in the well-studied S. cerevisiae, or brewer's yeast, but S. pombe seemed to have the right stuff.

Graduate student Adam Hughes then examined the role of these similar genes to prove that they in fact duplicate the human process. Indeed, the yeast gene they called sre1 triggered activation of cholesterol-producing genes, aided by a gene called scp1 that behaves like SCAP. As in humans, sre1 somehow gets turned on when cholesterol levels are low, increasing the cell's production of cholesterol. As cholesterol builds up in the cell, sre1 is gradually turned off. "Essentially, SREBP and sre1 both try to maintain an optimal level of cholesterol in the cells," says Espenshade.

But, based on what he now knows, Espenshade suspects that the yeast use cholesterol levels to figure out whether there's enough oxygen around for biology as usual. Single-celled yeast can alter their biology to live without oxygen, and human cells can do so to a certain extent. Johns Hopkins researcher Gregg Semenza, M.D., Ph.D., discovered a number of years ago how human cells react to low oxygen levels, but that process has never been connected to cholesterol production. "Our cells can adjust to lowered oxygen by turning on a specific set of genes when oxygen levels drop [using a gene called HIF1-alpha]," says Espenshade. "While there's no known connection between this process and cholesterol production, our results in the yeast suggest that perhaps SREBP itself, or something in the cholesterol pathway, might also serve as an oxygen sensor for mammalian cells."

It makes sense, he says, that the yeast could use its cholesterol levels as an indirect measure of oxygen levels. The cell uses a few oxygen molecules each time it makes cholesterol, so lowered cholesterol levels could signal that there's not enough oxygen around to make it. And because low cholesterol levels automatically turn on the yeast's version of SREBP, it's an easy solution to have the same gene sound the alarm that the cell needs to adapt to low levels of oxygen. Espenshade says sre1's role in the yeast's production of cholesterol (actually a similar molecule called ergosterol) and sensing of oxygen might offer a new opportunity to kill infectious yeast and fungi that share the gene with S. pombe.

"Without the sre1 gene, the yeast in our experiments died in low oxygen conditions," says Espenshade. "Because low oxygen levels are common in infected tissues, if we can block infectious yeasts' SREBP pathway without affecting human cells' cholesterol pathways, we might be able to treat certain infections." Espenshade and his team have found that infection-causing yeast Aspergillus, Neurospora, Cryptococcus and Ustilago share S. pombe's cholesterol-related genes, while S. cerevisae and the yeast Candida do not.


 

 


 


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