aging - gezond ouder worden en voeding


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Aging - gezond ouder worden


The sweet truth - Ditch sugar to look ten years younger

In a nutshell, sugar hastens the degradation of elastin and collagen, both key skin proteins. In other words, it actively ages you," says Dr Brandt, who counts Madonna, Rupert Everett, Cher and Ellen Barkin among his clients.

http://www.dailymail.co.uk/pages/live/femail/article.html?in_
article_id=461095&in_page_id=1879


Researchers at Illinois explore queen bee longevity

The researchers knew from studies of the fruit fly and nematode that the insulin-signaling pathway had a role in longevity. Down-regulation of insulin-IGF-1 signaling (IIS) in those species was associated with increases in longevity - but at the expense of fertility. They also knew that manipulating fat body cells in the head of the fruit fly influenced longevity. Because Vg is synthesized in fat body cells in honey bees, the team decided to look at Vg expression in the head and thorax as well as the abdomen.

http://www.news.uiuc.edu/news/07/0508queenbee.html


Low-calorie diet effective later in life

Reducing calorie intake later in life can still induce many health and longevity benefits, University of California researchers report.

http://www.upi.com/ConsumerHealthDaily/view.php?StoryID=20070404-052040-5628r


Lipoic acid explored as anti-aging compound

Researchers said today they have identified the mechanism of action of lipoic acid, a remarkable compound that in animal experiments appears to slow down the process of aging, improve blood flow, enhance immune function and perform many other functions.

http://www.eurekalert.org/pub_releases/2007-05/osu-lae051707.php


Corn, oats, cherries and red wine’s high melatonin content can help delay ageing

A study carried out by researchers from the University of Granada’s Institute of Biotechnology proves that consuming melatonin neutralizes oxidative damage and delays the neurodegenerative process of ageing. - In this study researchers used normal and genetically-modified mice which were subjected to accelerated cell ageing, although their results can also be applied to humans.

http://prensa.ugr.es/prensa/research/verNota/prensa.php?nota=427


Aging, Adiposity, and Calorie Restriction

Calorie restriction in adult men and women causes beneficial metabolic, hormonal, and functional changes, but the precise amount of calorie intake or body fat mass associated with optimalhealth and maximum longevity in humans is not known. In addition, it is possible that even moderate calorie restriction may be harmful in specific patient populations, such as lean persons who have minimalamounts of body fat.

http://jama.ama-assn.org/cgi/content/short/297/9/986?rss=1


Reducing insulin signaling in the brain can prolong lifespan

A study from Children's Hospital Boston finds that reducing insulin levels in the brain boosts longevity. Though it was done in genetically engineered mice, old-fashioned exercise and good diets also keep brain insulin levels low in humans.

http://www.childrenshospital.org/newsroom/Site1339/mainpageS1339P1sublevel325.html


Eat less, live longer, sure, but scientists want to know how

A team of scientists at the Pennington Biomedical Research Center recently made headlines by releasing strong results that indicate if you severely cut the calories you eat – by up to 25 percent for six months – while maintaining a nutritious diet, you are likely to be healthier and live longer. They dubbed the super diet “calorie restriction,” and now that same team wants local residents to help them learn how it works. Led by Eric Ravussin, Ph.D., the team learned that several “biomarkers” measured during calorie restriction indicated a slow down of the aging process. Participants were also healthier, but Ravussin doesn’t yet know what caused it. “All participants in the calorie restriction study ate less and exercised more, so they also lost weight. We’re not sure if their bodies reacted biologically to the decrease in calories or to the weight loss,” Ravussin said. “That’s what we’re trying to learn now, but we need help.”

http://www.pbrc.edu/News/News_Story.asp?id=69


Pennington Biomedical Research Center's Caloric Restriction Study

It has been reported for many years that sustained caloric restriction without nutritional deficiencies increases the length of life and prevents developement and/or progression of some age-related chronic diseases. The overall purpose of this study is to gain knowledge about the effects of two years of food restriciton in reducing the risk of disease associated with aging and in slowing the aging process.

http://calerie.pbrc.edu/introduction.html


Calorie Restriction Reduces Disease and Extends Life

In literally thousands of experiments, on a wide range of animals (almost certainly to include humans!), calorie restriction has greatly extended maximum and average lifespans and improved disease resistance, including resistance to many cancers. There is still uncertainty about why calorie restriction has these desired effects. Two important reasons proposed for the benefits of calorie restriction are: 1) fewer calories mean that there will be a reduction in the accumulation of oxidant and free-radical damage, and 2) fewer calories alter fat deposition, obesity, and hormones. The practical effect of this is improve the immune response of calorie-restricted (hereafter CR) animals. There are numerous reputable websites to learn more about the underlying animal studies (preliminary corroborative results are now coming out on the rhesus monkey experiments currently underway). Indeed, there are already convincing studies demonstrating the health benefits (and, no doubt, the longevity benefits…though not enough time has passed to observe these!) in humans. See the Sears and Walford references in the bibliography, and for a fascinating more general account of why we age check out Austad. For present purposes, that CR—with adequate or optimal nutrition (the first controversy)--is good for your prospects for a long, healthy life will be taken as a given. The science is unambiguous and the life extension benefits have been known (surprisingly) since 1935. The interesting questions revolve around related issues.

http://spot.colorado.edu/%7Egravesp/DietHealthandLongevity.html


The American Academy of Anti-Aging Medicine

A4M is a non-profit organization with a membership of 11,500 physicians and scientists from 65 countries, the American Academy of Anti-Aging Medicine (A4M) is an organization that is the sole medical society dedicated to the advancement of therapeutics related to the science of longevity medicine.

http://www.worldhealth.net/


Older Women Need A Little Meat On Their Bones

It's not a license to pig out, but a recent study found that women considered overweight by some measures had lower mortality than their skinnier counterparts. A study of more than 8,000 women ages 65 and older participating in the Study of Osteoporotic Fractures found those with body mass indexes (BMI) ranging from 24.6-29.8 kg/m2 had the lowest mortality. BMI charts typically place women with a BMI of 25-29.9 kg/m2 as overweight. [Ben Licher]

http://www.medicalnewstoday.com/medicalnews.php?newsid=65853&nfid=rssfeeds


The food additives 'that could put ten years on your life'

A visiting professor at Oxford University suggests that eating food enhanced with isotopes could be the holy grail of defying the ageing process.

http://www.dailymail.co.uk/pages/live/articles/health/
healthmain.html?in_article_id=444558&in_page_id=1774


Fight aging

We are on the verge of a revolution in medicine; understanding, treating, and ultimately preventing the causes of degenerative aging. But medical revolutions only happen if we all stand up in support of funding and research. We did it for cancer. We're doing it for Alzheimer's. We can do it for aging - and create an era of longer, healthier lives!"

http://www.fightaging.org/


Salk researchers discover first gene that specifically links calorie restriction to longevity

In studies going back to the 1930s, mice and many other species subsisting on a severely calorie-restricted diet have consistently outlived their well-fed peers by as much as 40 percent. But just how a diet verging on the brink of starvation extends lifespan has remained elusive.

http://www.salk.edu/news/releases/details_20070502b.php


Extreme dieting - Eat less, live longer?

Scientists believe they are a step closer to working out why an extremely restrictive diet boosts longevity. This well-documented calorie-cutting phenomenon has been seen in many species, from yeast to mice to dogs.

http://news.bbc.co.uk/1/hi/sci/tech/6617113.stm


 

 


 


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